Beechams Cold & Flu Tablets, Pain & Congestion Relief Medicine with Paracetamol, 16 tablets

Product Information

Pre-clinical safety data on these active ingredients in the literature have not revealed any pertinent and conclusive findings which are of relevance to the recommended dosage and use of the product and which have not already been mentioned elsewhere in this Summary. Adverse events of paracetamol from historical clinical trial data are both infrequent and from small patient exposure. Accordingly, events reported from extensive post-marketing experience at therapeutic/labelled dose and considered attributable are tabulated below by system class. The frequency of these adverse events is not known (cannot be estimated from available data).

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It must be noted that for clinically significant symptoms of caffeine overdose to occur with this product, the amount ingested would be associated with serious paracetamol-related liver toxicity. Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N- acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24h from ingestion should be discussed with the NPIS or a liver unit. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease. Underlying liver disease increases the risk of paracetamol-related liver damage. Evidence for cough syrups, however, is thin on the ground. They might offer some comfort at the time you take them, simply by coating the throat, but they'll have little to no effect on the natural course of the infection.It's fine to take Beechams flu plus caplets with plain ibuprofen or aspirin (assuming these are appropriate for you). However, don't take them with co-codamol, co-dydramol or Tramacet because these contain paracetamol. Overdose of caffeine may result in epigastric pain, vomiting, diurese, tachycardia or cardiac arrhythmia, CNS stimulation (insomnia, restlessness, excitement, agitation, jitteriness, tremors and convulsions). DO NOT TAKE MORE MEDICINE THAN THE LABEL TELLS YOU TO. IF YOU DO NOT GET BETTER, TALK TO YOUR DOCTOR. Consult your doctor: Before taking this medicine, if you are under the care of your doctor or receiving prescribed medicines or are pregnant. If you suffer from kidney or liver disease. Do not take with other flu, cold or decongestant products and avoid excessive intake of caffeine. Contains paracetamol. Do not take anything else containing paracetamol while taking this medicine. Talk to a doctor at once if you take too much of this medicine, even if you feel well. KEEP OUT OF THE SIGHT AND REACH OF CHILDREN. Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with the ingredients of Beechams flu plus caplets. Just because a side effect is stated here doesn't mean that all people using this medicines will experience that or any side effect.

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Guaifenesin is a type of medicine called a cough expectorant. Expectorants are used to treat a productive, chesty or mucus cough, where you cough up phlegm. Guaifenesin helps to thin and loosen the mucus in the airways, making it easier to cough up. Medical advice should be sought before taking this medicine in patients with: glutathione depletion due to metabolic deficiencies. If phenylephrine is taken with any of the following medicines, the combination may cause an increase in blood pressure. If you are already taking any of these medicines you should avoid taking this one as well: Excessive intake of caffeine (e.g. coffee, tea and some canned drinks) should be avoided while taking this product. Women who are pregnant. (Phenylephrine has blood vessel constricting effects that could restrict blood supply to the placenta, or cause problems for women with a history of pre-eclampsia. Ask your doctor or pharmacist for further advice on how to treat cold and flu symptoms during pregnancy.)

Do not take with any other paracetamol-containing products. Do not take with other flu, cold or decongestant products.

Beechams Flu Plus Caplets

Symptoms of paracetamol overdosage in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. Cardiac arrhythmias and pancreatitis have been reported. The body produces prostaglandins in response to injury and certain diseases. One of the effects of prostaglandins is to sensitise nerve endings, causing pain (presumably to prevent us from causing further harm to the area). As paracetamol reduces the production of these nerve sensitising prostaglandins it is thought it may increase our pain threshold, so that although the cause of the pain remains, we can feel it less. Don't take Beechams cold and flu capsules if you're taking any of the following medicines, because the combination may increase your blood pressure: An overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys. You should never exceed the dose stated in the information leaflet supplied with this medicine. Immediate medical advice should be sought in the event of an overdose with this medicine, even if you feel well, because of the risk of delayed, serious liver damage. Unfortunately, there aren't so many own-brand or generic versions of these around, so you'll usually have to pay a premium for them.Patients should be advised not to take other paracetamol-containing or other cold, flu or decongestant products concurrently. Medical advice should be sought if symptoms worsen, persist for more than 7 days, or are accompanied by high fever, skin rash or persistent headache. An overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys. Since the caplets contain caffeine, you should avoid drinking lots of caffeine-containing drinks, eg tea, coffee, cola, while you're taking them. Excessive caffeine consumption can cause insomnia, restlessness, anxiety, irritability, headaches and palpitations. One sachet to be taken every four to six hours as necessary. Do not exceed four sachets per 24 hours.