BEE VENOM CREAM - 30ml FAST RELIEF MUSCLE JOINT PAIN VERY EFFECTIVE

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Ko SH, Oh HM, Kwon DY, et al. Incidence Rate of Bee Venom Acupuncture Related Anaphylaxis: A Systematic Review. Toxins (Basel) 2022;14(4):238. View abstract. Pucca MB, Cerni FA, Oliveira IS, Jenkins TP, Argemí L, Sørensen C V. Bee updated: current knowledge on bee venom and bee envenoming therapy. Front Immunol. (2019) 10:2090. doi: 10.3389/fimmu.2019.02090 Duan K, Liu B, Li C, Zhang H, Yu T, Qu J, et al. Effectiveness of convalescent plasma therapy in severe COVID-19 patients. Proc Natl Acad Sci USA. (2020) 117:9490–6. doi: 10.1073/pnas.2007408117Conrad VJ, Hazan LL, Latorre AJ, Jakubowska A, Kim CMH. Efficacy and safety of honey bee venom (Apis mellifera) dermal injections to treat osteoarthritis knee pain and physical disability: a randomized controlled trial. J Altern Complement Med 2019;25(8):845-55. View abstract. Senel E, Holt S, Demir E. Treatment of notalgia paresthetica with bee venom and capsaicin: a pilot study with 20 patients. Skinmed 2019;17(6):370-2. View abstract. Shkenderov S, Koburova K. Adolapin-A newly isolated analgetic and anti-inflammatory polypeptide from bee venom. Toxicon. (1982) 20:317–21. doi: 10.1016/0041-0101(82)90234-3

Manuka Honey – Soothing, antibacterial and antioxidant properties which help fight premature ageing and healing of the skin.Simultaneously, cyclopeptide-5 acts to plump up fine lines and wrinkles and further freshens up the look of the eyes. Lim SM, Lee SH. Effectiveness of bee venom acupuncture in alleviating post-stroke shoulder pain: a systematic review and meta-analysis. J Integr Med. 2015;13(4):241-7. View abstract.

Stiffness and pain in the shoulder joint (frozen shoulder). Early research suggests that receiving dilute bee venom injections might improve pain and disability in people with frozen shoulder. But it doesn't seem to improve range of motion. Also, very dilute bee venom injects don't seem to be beneficial. Park JH, Kim JG, Cha SH, Park SD. Eosinophilic foreign body granuloma after multiple self-administered bee stings. Br J Dermatol 1998,139(6):1102-5. View abstract. Son D, Lee J, Lee Y, Song H, Lee C, Hong J. Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds. Pharmacol Ther. (2007) 115:246–70. doi: 10.1016/j.pharmthera.2007.04.004 Cho H-J, Jeong Y-J, Park K-K, Park Y-Y, Chung I-K, Lee K-G, et al. Bee venom suppresses PMA-mediated MMP-9 gene activation via JNK/p38 and NF-κB-dependent mechanisms. J Ethnopharmacol. (2010) 127:662–8. doi: 10.1016/j.jep.2009.12.007 Wesselius T, Heersema DJ, Mostert JP, et al. A randomized crossover study of bee sting therapy for multiple sclerosis. Neurology 2005;65:1764-8. View abstract.

All authors listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication. Funding A leading adjuvant of SARS-CoV-2 therapies currently being promoted is aluminum hydroxide due to its slow release and increased interaction with antigen presenting cells ( 115). Bee venom offers a candidate for control SARS-CoV-2 infections and could offer advantages against COVID-19. PLA 2 has been associated with a level of success against SARS-CoV-2 infections ( 116, 117). Conjugation of BV peptides could offer a new approach in the development of the BV vaccine. Potential Relationship Between Bee Venom Proteins and COVID-19 Proteins Be cautious with this combination • Medications that decrease the immune system (Immunosuppressants) interacts with BEE VENOM of Biosystems Engineering, Faculty of Environmental Engineering and Mechanical Engineering, Poznan University of Life Sciences, Poznan, Poland Rady I, Siddiqui IA, Rady M, Mukhtar H. Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy. Cancer Lett. (2017) 402:16–31. doi: 10.1016/j.canlet.2017.05.010

Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, JapanTaketomi Y, Ueno N, Kojima T, Sato H, Murase R, Yamamoto K, et al. Mast cell maturation is driven via a group III phospholipase A 2-prostaglandin D2-DP1 receptor paracrine axis. Nat Immunol. (2013) 14:554–63. doi: 10.1038/ni.2586 Mozzini C, Girelli D. The role of neutrophil extracellular traps in Covid-19: only an hypothesis or a potential new field of research? Thromb Res. (2020) 191:26–7. doi: 10.1016/j.thromres.2020.04.031 Kim K, Jeong H, Lee G, Jang S, Yook T. Characteristics of Adverse Events in Bee Venom Therapy Reported in South Korea: A Survey Study. Toxins (Basel) 2021;14(1):18. View abstract.