Bee Health Propolis Lozenges 114 g Pack of 2

Product Information

Martinotti S, Ranzato E. Propolis: A new frontier for wound healing? Burns & Trauma. 2015;3:s41038-015-0010-z. doi:10.1186/s41038-015-0010-z Santos, V. R., Pimenta, F. J., Aguiar, M. C., do Carmo, M. A., Naves, M. D., and Mesquita, R. A. Oral candidiasis treatment with Brazilian ethanol propolis extract. Phytother Res 2005;19(7):652-654. View abstract. Metzner, J., Bekemeier, H., Paintz, M., and et al. [On the antimicrobial activity of propolis and propolis constituents (author's transl)]. Pharmazie 1979;34(2):97-102. View abstract. Martinez, Silveira G., Gou, Godoy A., Ona, Torriente R., and et al. [Preliminary study of the effects of propolis in the treatment of chronic gingivitis and oral ulceration]. Rev Cubana Estomatol. 1988;25(3):36-44. View abstract. When applied to the skin: Propolis is possibly safe when used appropriately. It can cause allergic reactions, especially in people who are allergic to other bee products. Pregnancy: There isn't enough reliable information to know if propolis is safe to use when pregnant. Stay on the safe side and avoid use.

Diabetes is a serious condition that affects your body’s ability to properly maintain your blood sugar levels. Some studies suggest that propolis may help with this. Hartwich, A., Legutko, J., and Wszolek, J. [Propolis: its properties and administration to patients treated for some surgical diseases]. Przegl.Lek. 2000;57(4):191-194. View abstract. Li YJ, Lin JL, Yang CW, Yu CC. Acute renal failure induced by a Brazilian variety of propolis. Am J Kidney Dis 2005;46:e125-9. View abstract. Xuan H, Li Z, Yan H, et al. Antitumor activity of Chinese propolis in human breast cancer mcf-7 and mda-mb-231 cells. Evidence-Based Complementary and Alternative Medicine. 2014;2014:1-11. doi:10.1155/2014/280120 For example, gastritis and peptic ulcers are often caused by the overgrowth of the bacteria H. pylori. Studies suggest that consuming propolis, with or without honey, can help reduce the symptoms of gastritis and peptic ulcers significantly. Propolis may even encourage healing.Debiaggi, M., Tateo, F., Pagani, L., and et al. Effects of propolis flavonoids on virus infectivity and replication. Microbiologica 1990;13(3):207-213. View abstract. Data from studies concerning antibacterial properties of propolis support the fact that propolis is active mainly against Gram-positive bacteria in and shows lower activity against the Gram-negative ones at small quantity or is inactive at all [ 7, 35, 37– 41]. Such results can be seen in the work of Kujumgiev et al. (1999) who tested propolis samples from different geographic regions (tropical and temperate zones) against Staphylococcus aureus and Escherichia coli. All the extracts displayed significant antibacterial activity against S. aureus but none was active against E. coli; it is also relevant that all the 12 samples tested, from different origins, showed the same effect. Lee SK, Song L, Mata-Greenwood E, et al. Modulation of in vitro biomarkers of the carcinogenic process by chemopreventive agents. Anticancer Res 1999;19:35-44. View abstract. Halboub E, Al-Maweri SA, Al-Wesabi M, et al. Efficacy of propolis-based mouthwashes on dental plaque and gingival inflammation: A systematic review. BMC Oral Health. 2020;20(1):198. doi:10.1186/s12903-020-01185-5

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Volpert, R. and Elstner, E. F. Interactions of different extracts of propolis with leukocytes and leukocytic enzymes. Arzneimittelforschung 1996;46(1):47-51. View abstract.Afkhamizadeh M, Aboutorabi R, Ravari H, et al. Topical propolis improves wound healing in patients with diabetic foot ulcer: a randomized controlled trial. Nat Prod Res. 2018;32(17):2096-2099. View abstract. Boyanova, L., Kolarov, R., Gergova, G., and Mitov, I. In vitro activity of Bulgarian propolis against 94 clinical isolates of anaerobic bacteria. Anaerobe. 2006;12(4):173-177. View abstract. Chan GCF, Cheung KW, Sze DMY. The immunomodulatory and anticancer properties of propolis. Clinic Rev Allerg Immunol. 2013;44(3):262-273.

Arenberger P, Arenbergerova M, Hladíková M, Holcova S, Ottillinger B. Comparative Study with a Lip Balm Containing 0.5% Propolis Special Extract GH 2002 versus 5% Aciclovir Cream in Patients with Herpes Labialis in the Papular/Erythematous Stage: A Single-blind, Randomized, Two-arm Study. Curr Ther Res Clin Exp. 2017;88:1-7. View abstract. The antitumor activity of propolis was reviewed by Orsolic et al. The chemopreventive activity of propolis in animal models and cell cultures is likely to be the result of their ability to inhibit DNA synthesis in tumour cells, their capability to induce apoptosis of tumour cells, and their property to activate macrophages to produce factors capable of regulating the function of B, T and NK cells, respectively. Moreover, these results suggest that flavonoids from propolis play a protective role against the toxicity of the chemotherapeutic agents or radiation in mice, giving hope that they may have similar protective action in humans. The combination with an adjuvant antioxidant therapy may enhance the effectiveness of chemotherapy by ameliorating the side effect on leukocytes, liver, and kidneys and consequently enabling dose escalation [ 63]. Although many polyphenols have an antimetastatic activity, caffeic acid phenethyl esters (CAPE) from poplar propolis and Artepillin C from Baccharis propolis have been identified as the most potent antitumor agents [ 64– 68]. Propolis is a complex mixture made by bee-released and plant-derived compounds. In general, raw propolis is composed of around 50% resins, 30% waxes, 10% essential oils, 5% pollen, and 5% of various organic compounds [ 1, 8, 9]. More than 300 constituents were identified in different samples [ 7– 10] and new ones are still being recognized during chemical characterization of new types of propolis [ 2, 11, 12]. The proportions of the various substances present in the propolis depend upon its place and time of collection. The major allergens in propolis derived from poplar buds are caffeates. 3-Methyl-2-butenyl caffeate and phenylethyl caffeate are the main sensitisers. Benzyl caffeate, geranyl caffeate, benzyl salicylate, benzyl cinnamate, methyl cinnamate, ferulic acid and tectochrysin are also sensitisers present in propolis. Banskota, A. H., Tezuka, Y., Adnyana, I. K., and et al. Cytotoxic, hepatoprotective and free radical scavenging effects of propolis from Brazil, Peru, the Netherlands and China. J Ethnopharmacol. 2000;72(1-2):239-246. View abstract.Schmidt, H., Hampel, C. M., Schmidt, G., and et al. [Double-blind trial of the effect of a propolis-containing mouthwash on inflamed and healthy gingiva]. Stomatol.DDR. 1980;30(7):491-497. View abstract. Roy et al. extended pinocembrin and galangin in the rapid synthesis of stable Ag and Au nanoparticles having wide spectrum of fascinating morphologies. Both of these two extracts were found to be extremely efficient in the synthesis of Ag and Au nanoparticles under alkaline condition for a given metal ion precursor; the kinetics of a particle synthesis were remarkably similar in all the cases, as it is evident from the absorption spectra monitored over time [ 19]. Pasupuleti VR, Sammugam L, Ramesh N, Gan SH. Honey, propolis, and royal jelly: a comprehensive review of their biological actions and health benefits. Oxid Med Cell Longev. 2017;2017:1259510. doi:10.1155/2017/1259510