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Becoming the Bimboy (Bimbo Transformation Story, Gay Alpha Male M/M Romance)

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AB - Substitution of fossil fuels by sustainable practices must be rapidly implemented to mitigate the impacts of climate change. The conversion of biomass into combustible gas is investigated in a microwave-induced plasma reactor using pure steam as the plasma working gas for the first time. The optimum results are achieved at the highest forward microwave power of 6 kW with biomass carbon conversion efficiency over 98% and complete biomass energy recovery in syngas. Unreacted steam is simply condensed out, leading to the production of a syngas with low inert dilution and high calorific value in the range 10.5–12 MJ/Nm3. The syngas produced is rich in hydrogen, exceeding 60% by volume. The proposed process could aid in the transition to a carbon neutral economy as it has the potential to efficiently convert biomass to syngas that can be used for the sustainable generation of fuels, chemicals and energy.

M. Mahmoudi, I. Lynch, M. R. Ejtehadi, M. P. Monopoli, F. B. Bombelli and S. Laurent, Chem. Rev., 2011, 111, 5610–5637 CrossRef CAS PubMed. This took place after Kelly asked Trump a question that referenced his television show The Apprentice from season 6 in 2005. Shortly afterwards, Stephen Richter of The Globalist published an opinion piece in which he accused Trump of being a bimbo, noting the original definition of bimbo as "an unintelligent or brutish male". [17] See also [ edit ]

bim·bo

H. A. Santos, L. M. Bimbo, V.-P. Lehto, A. J. Airaksinen, J. Salonen and J. Hirvonen, Curr. Drug Discovery Technol., 2011, 8, 228–249 CrossRef CAS. A. S. Utada, L.-Y. Chu, A. Fernandez-Nieves, D. R. Link, C. Holtze and D. A. Weitz, MRS Bull., 2007, 32, 702–708 CrossRef CAS.

Parents concerned about Miss Bimbo game". Daily Telegraph. London. 2008-03-25. Archived from the original on 2008-03-25 . Retrieved 2008-03-25. To test the potential of THCPSiMPs–lipid vesicles for drug delivery applications, the THCPSiMPs were loaded with a model drug, piroxicam. This drug belongs to the Biopharmaceutical Classification System class II, i.e. it is highly hydrophobic, poorly water-soluble and highly permeable across biological membranes. To load piroxicam, the THCPSiMPs were stirred in an acetone solution of piroxicam at 15 mg mL −1 for 2 h. Then, the suspension was centrifuged at 11 300 × g for 4 min and the pellet was washed 3 times with 0.5 mL of MilliQ-water; water allows the removal of the excess piroxicam from the surface of the particles, while avoiding a premature release of the drugs from the pores. Finally, the loaded microparticles were suspended into the inner water phase and the production proceeded as described previously.M. Kovalainen, J. Mönkäre, E. Mäkilä, J. Salonen, V.-P. Lehto, K.-H. Herzig and K. Järvinen, Pharm. Res., 2012, 29, 837–846 CrossRef CAS PubMed.

Mesoporous materials, particularly porous silicon (PSi), have recently emerged as a promising platform for drug delivery 11–15 and imaging 11,15,16 applications. PSi is a material traversed by nanoscale pores in the crystalline Si structure, encompassing several attractive physical properties, such as top-down manufacturing, 11,12,17 fine-tunable nanoscale size, high surface-to-volume ratio, as well as large surface area and pore volume. 11,12,14 The PSi mesoporous structure has been proven to enable efficient loading of multiple therapeutic agents within its pores, including poorly water-soluble drugs, 12,18–23 peptides, 24–26 and siRNA, 27,28 with optimized and reproducible dissolution and release profiles. Additionally, PSi is characterized by suitable biocompatibility, 18,19,29–31 biodegradability in non-toxic products 15,30–32 and easy surface modification. 12,33 L. R. Arriaga, S. S. Datta, S.-H. Kim, E. Amstad, T. E. Kodger, F. Monroy and D. A. Weitz, Small, 2013 DOI: 10.1002/smll.201301904. The FTIR spectra of HA, HA +, UnTHCPSi and UnTHCPSi–HA + nanoparticles are presented in Fig. 1C. The carbohydrate chain of HA can be identified through the prominent C–O band at 900–1200 cm −1, which is a characteristic of polysaccharides. Other observable features of HA are the stretching bands at 1607 cm −1 ( Fig. 1C-a 2) and 1400 cm −1 ( Fig. 1C-a 4), related to the carboxylate C O and C–O stretching vibrations, respectively. The amide I and II related bands on the other hand, are visible at ca. 1670 cm −1 ( Fig. 1C-a1) and 1540 cm −1 ( Fig. 1C-a 3), respectively. 58,59 The effects of amine modification of the HA + have only limited visible effects on the spectra ( Fig. 1C-b). The basic chemical structure of HA is preserved during the modification, however the appearance of a broad band at ca. 1680 cm −1 ( Fig. 1C-b1) and a peak at 1555 cm −1 ( Fig. 1C-b 2) indicate the presence of the amide-conjugated NH 2-PEG 2-NHBoc in the polymer. The spectra of the UnTHCPSi nanoparticles ( Fig. 1C-d) exhibit a broad band between 900 and 1200 cm −1 and a C O stretching at 1715 cm −1 ( Fig. 1C-d1), corresponding to the Si–C and carboxylic acid group structures, respectively. After functionalization of the UnTHCPSi nanoparticle surface with HA + polymer ( Fig. 1C-c), and compared to the bare UnTHCPSi spectrum, a broad absorption band corresponding to the amide (I) structure arises at 1640 cm −1 ( Fig. 1C-c1) and the amide (II) structure of HA + can be recognized at 1555 cm −1, suggesting the successful covalent attachment of the polymer. The described analysis indicated that the HA + polymer was successfully synthesized by the EDC/NHS reaction and conjugated onto the surface of the UnTHCPSi nanoparticles via the same carbodiimide-mediated coupling chemistry. Stability in human plasma When an intravenous administration is envisioned, the interaction of plasma proteins with a nanoparticulate system may influence its biofate. H. Ponta, L. Sherman and P. A. Herrlich, Nat. Rev. Mol. Cell Biol., 2003, 4, 33–45 CrossRef CAS PubMed.A. M. DiLauro, A. Abbaspourrad, D. A. Weitz and S. T. Phillips, Macromolecules, 2013, 46, 3309–3313 CrossRef CAS. C. Chiappini, E. Tasciotti, J. R. Fakhoury, D. Fine, L. Pullan, Y. Wang, L. Fu, X. Liu and M. Ferrari, ChemPhysChem, 2010, 11, 1029–1035 CrossRef CAS PubMed. K. Haxaire, Y. Maréchal, M. Milas and M. Rinaudo, Biopolymers, 2003, 72, 10–20 CrossRef CAS PubMed. M.-A. Shahbazi, M. Hamidi, E. M. Mäkilä, H. Zhang, P. V. Almeida, M. Kaasalainen, J. J. Salonen, J. T. Hirvonen and H. A. Santos, Biomaterials, 2013, 34, 7776–7789 CrossRef CAS PubMed. Valley girl and Essex girl carry similar connotations to a young bimbo or "bimbette", but are non-synonymous.

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