OxiPro OX2 - CE Certified - MHRA Registered Pulse Oximeter / Blood Oxygen Monitor - Finger Oxygen Saturation Monitor / SATS Monitor SpO2 for Adults and Child - UK Approved Medical Device

Product Information

The opioid drug withdrawal syndrome is characterised by some or all of the following: restlessness, lacrimation, rhinorrhoea, yawning, perspiration, chills, myalgia, mydriasis and palpitations. Other symptoms may also develop including irritability, agitation, anxiety, hyperkinesia, tremor, weakness, insomnia, anorexia, abdominal cramps, nausea, vomiting, diarrhoea, increased blood pressure, increased respiratory rate or heart rate. These tablets may cause a number of side effects such as drowsiness which could affect your ability to drive or use machinery (see section 4 for a full list of side effects). These are usually most noticeable when you first start taking the tablets, or when changing to a higher dose. If you are affected you should not drive or use machinery. Taking this medicine regularly, particularly for a long time, can lead to dependence, abuse and addiction which may result in life-threatening overdose. The risk of these side effects can increase with a higher dose and longer duration of use. Your prescriber should have explained how long you will be taking it for and when it is appropriate to stop, how to do this safely. Oxycodone may impair the ability to drive and use machines. This is particularly likely at the beginning of the treatment with Oxypro, after dose increase or change of product and if Oxycodone is combined with other CNS depressant agents.

Naloxone: e.g., 0.4-2 mg intravenous. Administration of single doses must be repeated depending on the clinical situation at intervals of 2 to 3 minutes. Intravenous infusion of 2 mg of naloxone in 500 ml isotonic saline or 5% dextrose solution (corresponding to 0.004 mg naloxone/ml) is possible. The rate of infusion should be adjusted to the previous bolus injections and the response of the patient. In the year of pandemic and coronavirus, the best oximeter in UK is a basic need of all our household! Concomitant administration of oxycodone with serotonin agents, such as a Selective Serotonin Re-uptake Inhibitor (SSRI) or a Serotonin Norepinephrine Re-uptake Inhibitor (SNRI) may cause serotonin toxicity. The symptoms of serotonin toxicity may include mental-status changes (e.g., agitation, hallucinations, coma), autonomic instability (e.g., tachycardia, labile blood pressure, hyperthermia), neuromuscular abnormalities (e.g., hyperreflexia, incoordination, rigidity), and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhoea). Oxycodone should be used with caution and the dosage may need to be reduced in patients using these medications. Grapefruit Juice, a CYP3A4 inhibitor, administered as 200 ml three times a day for five days, increased the AUC of oral oxycodone. On average, the AUC was approximately 1.7 times higher (range 1.1 - 2.1). The blood pressure monitor can be used by up to two users, storing 99 results for each user independently.

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Accurate & Reliable Monitor You Can Trust】Built-in advanced sensor & updated algorithms, the upper arm blood pressure machine has been verified by tens of thousands of clinical trials to provide best performance and more accurate results. High-precision, blood pressure±3mmHg, pulse±5%. A color scale indicator on the screen for WHO guidelines easily interprets whether the blood pressure is high or low. The airways must be kept clear. Pure opioid antagonists such as naloxone are specific antidotes against symptoms of opioid overdose. Other supportive measures should be employed as needed. Especially in high dosages you may experience increased sensitivity to pain (hyperalgesia) despite the fact that you are taking increasing doses of Oxypro. Your prescriber will decide whether you need a change in dose or a change in strong analgesic (opioids).

Pulse oximeters are usually used in clinical settings, such as GP surgeries and hospitals, but can also be useful at-home monitoring tools for individuals suffering from chronic obstructive pulmonary disease, lung cancer and other conditions. NHS SUPPLIED AND CE CERTIFIED MEDICAL BLOOD PRESSURE MONITOR (Sphygmomanometer) Used by the Royal Berkshire NHS Trust for their Home Blood Pressure Monitor program (note this does not constitute endorsement or that the product is NHS approved). INCLUDES ACCESSORIES - Include 2X AAA BATTERIES that will allow you to use the pulse oximeter right out of the box and a LANYARD for convenience. Use of opioids including Oxypro and sedative medicines such as benzodiazepines or related drugs together increases the risk of drowsiness, difficulties in breathing (respiratory depression), coma and may be life-threatening. Because of this, concomitant use should only be considered when other treatment options are not possible. Tell your prescriber if you are taking/using, have recently taken/used or might take/use any other medicines, including medicines obtained without a prescription.Oxycodone is metabolised mainly by CYP3A4, with a contribution from CYP2D6. The activities of these metabolic pathways may be inhibited or induced by various co-administered drugs or dietary elements. The following sections explain these interactions in more detail. In patients with low body weight or in slow metabolisers who are also opioid-naive, the recommended starting dose should be reduced to half of the recommended starting dose for adults. Therefore the lowest recommended dosage mentioned in this SmPC i.e. 10 mg, may not be suitable as a starting dose. In this case Oxypro 5 mg prolonged release tablets should be used.

The concomitant use of opioids with sedative medicines such as benzodiazepines or related drugs increases the risk of sedation, respiratory depression, coma, and death because of additive CNS depressant effect. The dose and duration of concomitant use should be limited (see section 4.4). Drugs affecting the central nervous system (CNS) include other opioids, gabapentinoids such as pregabalin, anxiolytics, sedatives hypnotics (including benzodiazepines), antipsychotics, antidepressants, phenothiazines and alcohol. CYP3A4 inducers, such as rifampicin, carbamazepin, phenytoin or St John´s Wort may induce the metabolism of oxycodone and cause an increased clearance of oxycodone that could cause a reduction of the plasma concentrations of oxycodone. The oxycodone dose may need to be adjusted accordingly. Some specific examples of CYP3A4 enzyme inducer are provided below: The use of Oxypro may lead to positive results for doping controls. Use of Oxypro as a doping agent may become a health hazard. The OxiPro finger tip pulse oximeter is a CE Class II Medical Device and BS-EN-ISO-80601-2-61 tested meaning it is suitable for use both in clinical and home environments for blood oxygen monitoring and is

Interaction

if you have a thyroid disease where the skin on the face and limbs is pasty, swollen, cool and dry, Dependence or addiction can make you feel that you are no longer in control of how much medicine you need to take or how often you need to take it. You might feel that you need to carry on taking your medicine, even when it doesn’t help to relieve your pain.