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APIDERMIN FACE MOISTURIZER CREAM WITH ROYAL JELLY & VITAMIN A - Dry, Tired & Wrinkled skin

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efectele binefăcătoare ale cerii naturale de albine sunt cunoscute de mii de ani în cosmetică datorită proprietăților sale de vindecare Pek, J. W., Lim, A. K. & Kai, T. Drosophila maelstrom ensures proper germline stem cell lineage differentiation by repressing microRNA-7. Dev. Cell 17, 417–424 (2009). Kim, C.R.; Kim, J.M.; Choi, H.Y.; Choi, Y.S.; Jin, B.R.; Lee, K.S.; Choi, K.H. Analysis of the gut microbiome of susceptible and resistant honeybees ( Apis cerana) against sacbrood virus disease. J. Appl. Entomol. 2022. Early View. [ Google Scholar] [ CrossRef]

Nouvian, M., Reinhard, J. & Giurfa, M. The defensive response of the honeybee Apis mellifera. J. Exp. Biol. 219, 3505–3517 (2016). Yang, H., Basquin, D., Pauli, D. & Oliver, B. Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. BMC Genomics 18, 1–13 (2017).Bull, J. C. et al. A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees. PLoS Pathog. 8, e1003083 (2012). Grozinger, C. M., Sharabash, N. M., Whitfield, C. W. & Robinson, G. E. Pheromone-mediated gene expression in the honey bee brain. Proc. Natl. Acad. Sci. 100, 14519–14525 (2003).

lăptișorul de matcă reprezintă o substanță naturală cu numeroase principii nutritive, fiind un concentrat biologic bogat în substanțe proteice: lipide, glucide și vitamine Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15(12):550. https://doi.org/10.1186/s13059-014-0550-8. Among the entire gene expressions of different organs from each caste, we investigated the expression ratio of immune-response genes relative to whole transcripts. In comparing the gene expressions, which are displayed in Fig. 4a, the rate of the expression of immune-related genes was different in each organ, which implies that these genes were mainly abundant in the intestinal organs (Fig. 4b). In comparing the transcriptome profiles of whole organs, queen exhibited weakest innate immune-related genes expressed in natural conditions (Fig. 4c). Expression of detoxification machinery Ward, R.; Coffey, M.; Kavanagh, K. Proteomic analysis of summer and winter Apis mellifera workers shows reduced protein abundance in winter samples. J. Insect Physiol. 2022, 139, 104397. [ Google Scholar] [ CrossRef]Lee, K.S.; Kim, B.Y.; Yoon, H.J.; Choi, Y.S.; Jin, B.R. Secapin, a bee venom peptide, exhibits anti-fibrinolytic, anti-elastolytic, and anti-microbial activities. Dev. Comp. Immunol. 2016, 63, 27–35. [ Google Scholar] [ CrossRef] [ PubMed]

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