Lattoferrina 200 Immuno 30 Stick Pack PromoPharma

Product Information

Gao Y, Hou L, Lu C, et al. Enteral lactoferrin supplementation for preventing sepsis and necrotizing enterocolitis in preterm infants: A meta-analysis with trial sequential analysis of randomized Controlled Trials. Front Pharmacol. 2020 Aug 7;11:1186. View abstract.

Abbondantissima nel colostro umano o primo latte, la lattoferrina circola nell'organismo prevalentemente nel plasma sanguigno. Okada S, Tanaka K, Sato T, et al. Dose-response trial of lactoferrin in patients with chronic hepatitis C. Jpn J Cancer Res 2002;93:1063-9. View abstract. Andrés MT, Fierro JF (October 2010). "Antimicrobial mechanism of action of transferrins: selective inhibition of H+-ATPase". Antimicrobial Agents and Chemotherapy. 54 (10): 4335–42. doi: 10.1128/AAC.01620-09. PMC 2944611. PMID 20625147. a b Broc JH, De Sousa M (1989). Iron in immunity, cancer, and inflammation. New York: Wiley. ISBN 978-0-471-92150-9. Il recettore della lattoferrina svolge un ruolo importante nella captazione della stessa ne facilita il legame con gli ioni ferro.Berthon BS, Williams LM, Williams EJ, Wood LG. Effect of Lactoferrin Supplementation on Inflammation, Immune Function, and Prevention of Respiratory Tract Infections in Humans: A Systematic Review and Meta-analysis. Adv Nutr 2022;13(5):1799-1819. View abstract. Singh PK, Parsek MR, Greenberg EP, Welsh MJ (May 2002). "A component of innate immunity prevents bacterial biofilm development". Nature. 417 (6888): 552–5. Bibcode: 2002Natur.417..552S. doi: 10.1038/417552a. PMID 12037568. S2CID 4423528. Jellin JM, Batz F, Hitchens K (2007). Natural Medicines Comprehensive Databas (10thed.). Therapeutic Research Faculty. p.915. ISBN 978-0-9788205-3-4. Both in blood plasma and in secretory fluids lactoferrin can exist in different polymeric forms ranging from monomers to tetramers. Lactoferrin tends to polymerize both in vitro and in vivo, especially at high concentrations. [25] Several authors found that the dominant form of lactoferrin in physiological conditions is a tetramer, with the monomer:tetramer ratio of 1:4 at the protein concentrations of 10 −5 M. [27] [28] [29]

Motoki N, Mizuki M, Tsukahara T, et al. Effects of lactoferrin-fortified formula on acute gastrointestinal symptoms in children aged 12-32 months: A randomized, double-blind, placebo-controlled trial. Front Pediatr. 2020 May 19;8:233. View abstract. Lactoferrin supplements reduce the risk of respiratory tract infections, based on a recent meta-analysis of randomized controlled trials. [9] As with any supplements sold online, quality may be an issue because nutritional supplement production quality controls are not subject to the same strict regulatory process as medicines. [10] History [ edit ] Di Mario F, Aragona G, Dal Bo N, et al. Use of bovine lactoferrin for Helicobacter pylori eradication.Dig Liver Dis 2003;35:706-10. . View abstract.

Proprietà

Vetrugno V. Safety of milk and milk derivatives in relation to BSE: the lactoferrin example. Biometals 2004;17:353-6. View abstract. Ochoa TJ, Loli S, Mendoza K, et al. Effect of bovine lactoferrin on prevention of late-onset sepsis in infants <1500g: a pooled analysis of individual patient data from two randomized controlled trials. Biochem Cell Biol. 2020 Sep 15. View abstract. Nakano M, Yoshida A, Wakabayashi H, et al. Effect of tablets containing lactoferrin and lactoperoxidase on gingival health in adults: A randomized, double-blind, placebo-controlled clinical trial. J Periodontal Res. 2019 Dec;54(6):702-708. View abstract. Muscedere J, Maslove DM, Boyd JG, et al. Prevention of nosocomial infections in critically ill patients with lactoferrin: A randomized, double-blind, placebo-controlled study. Crit Care Med. 2018 Sep;46(9):1450-1456. View abstract. Chang R, Ng TB, Sun WZ (September 2020). "Lactoferrin as potential preventative and adjunct treatment for COVID-19". International Journal of Antimicrobial Agents. 56 (3): 106118. doi: 10.1016/j.ijantimicag.2020.106118. PMC 7390755. PMID 32738305.

Birgens HS (April 1985). "Lactoferrin in plasma measured by an ELISA technique: evidence that plasma lactoferrin is an indicator of neutrophil turnover and bone marrow activity in acute leukaemia". Scandinavian Journal of Haematology. 34 (4): 326–31. doi: 10.1111/j.1600-0609.1985.tb00757.x. PMID 3858982. In another study considering the saliva analysis of COVID-19 patients ( 102), three groups of participants were selected, which were either non-infected or infected before 7 days or recovered from the virus for at least 2 months. All saliva samples of participants were analyzed by real-time PCR for the detection of SARS-CoV-2. In addition, several parameters including TNF-α, IL-6, IL-10 (Cytokines), Lf, lysozyme, IgG, IgA, and IgM were analyzed by the ELISA method. In the results, the Lf amount was recorded lower in the infected patients when compared with the non-infected group. This indicates that there might be a relationship between the observed cytokine storm—an aggressive inflammatory response—and a decrease of Lf in the COVID-19 patients. The indication is also supported in another review article about Lf's potential reducing effect on SARS-CoV-2 induced cytokine storm ( 15). Lf's immune system modulating function might control the excessive stimulation of immune system that is led to creation of cytokine storm. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Publisher's noteLactoferrin supplements could aid in the recovery of COVID19 & other Respiratory Tract Infections". EurekAlert! . Retrieved 2022-02-18. Harmsen MC, Swart PJ, de Bethune MP, et al. Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro. J Infect Dis 1995;172:380-8. View abstract. Fujihara T, Hayashi K (1995). "Lactoferrin inhibits herpes simplex virus type-1 (HSV-1) infection to mouse cornea". Archives of Virology. 140 (8): 1469–1472. doi: 10.1007/BF01322673. PMID 7661698. S2CID 4396295.

Tsukahara T, Fujimori A, Misawa Y, et al. The preventive effect of lactoferrin-containing yogurt on gastroenteritis in nursery school children-intervention study for 15 weeks. Int J Environ Res Public Health. 2020 Apr 7;17(7):2534. View abstract. Russo R, Superti F, Karadja E, De Seta F. Randomised clinical trial in women with recurrent vulvovaginal candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment. Mycoses. 2019 Apr;62(4):328-335. View abstract. Per esaminare in che modo la lattoferrina possa influire sulle ossa, è stata utilizzata in forma arricchita con ribonucleasi. Levay PF, Viljoen M (January 1995). "Lactoferrin: a general review". Haematologica. 80 (3): 252–67. PMID 7672721. Saraceno R, Gramiccia T, Chimenti S, Valenti P, Pietropaoli M, Bianchi L. Topical lactoferrin can improve stable psoriatic plaque. G Ital Dermatol Venereol. 2014;149(3):335-40. View abstract.

Lactoferrin Transport

Mantel C, Miyazawa K, Broxmeyer HE (1994). "Physical characteristics and polymerization during iron saturation of lactoferrin, a myelopoietic regulatory molecule with suppressor activity". Lactoferrin Structure and Function. Advances in, Experimental Medicine and Biology. Vol.357. pp.121–32. doi: 10.1007/978-1-4615-2548-6_12. ISBN 978-0-306-44734-1. PMID 7762423. Bharadwaj S, Naidu AG, Betageri GV, Prasadarao NV, Naidu AS (September 2009). "Milk ribonuclease-enriched lactoferrin induces positive effects on bone turnover markers in postmenopausal women". Osteoporosis International. 20 (9): 1603–11. doi: 10.1007/s00198-009-0839-8. PMID 19172341. S2CID 10711802. Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. a b c Nozaki A, Ikeda M, Naganuma A, Nakamura T, Inudoh M, Tanaka K, Kato N (March 2003). "Identification of a lactoferrin-derived peptide possessing binding activity to hepatitis C virus E2 envelope protein". The Journal of Biological Chemistry. 278 (12): 10162–10173. doi: 10.1074/jbc.M207879200. PMID 12522210. Xavier PL, Chaudhari K, Verma PK, Pal SK, Pradeep T (December 2010). "Luminescent quantum clusters of gold in transferrin family protein, lactoferrin exhibiting FRET" (PDF). Nanoscale. 2 (12):